Axillo-Subclavian Vein Thrombosis

Symptoms and risk factors of a Paget-Schroetter syndrome

Axillo-subclavian vein thrombosis develops when a rib or a nearby muscle presses on the axillary vein in the armpit or the subclavian vein in front of the shoulder. This rare condition is a type of thoracic outlet syndrome (TOS) caused by repetitive arm motion, particularly in athletes.

Repeated compression causes the vein to become inflamed and fibrous tissue to build up. This tissue causes the vein to narrow and restrict blood flow, leading to the formation of blood clots.

Left untreated, axillo-subclavian vein thrombosis can cause:

• Arm pain and fatigue
• Arm swelling
• Chronic venous insufficiency
• Pulmonary Hypertension

The specialists in our Vascular and Endovascular Program are leaders in treating venous issues with minimally invasive techniques.

What are the symptoms?

Symptoms can be vague until the vein is fairly blocked. At that time, you may experience:

• Bluish skin color
• Heaviness of the arm
• Muscle bulk that doesn’t match the other arm
• Swelling and pain in the arm

Who is at risk?

The condition can affect anyone, but you are at increased risk if you:

• Participate in sports that require repetitive arm and shoulder motions, such as baseball, softball, basketball, hockey, swimming, tennis and weightlifting
• Work in occupations that involve repetitive use of the arm, such as construction work, house painting or window washing
• Have a blood clotting disorder
• Have a central venous catheter in the subclavian vein, such as for chemotherapy or hemodialysis
• Have a pacemaker or defibrillator, because the wires pass through the area

Tests

Treatments

In the early stages of axillo-subclavian vein thrombosis, medication may be successful to dissolve clots (thrombolysis). In some cases, surgery may be recommended to restore blood flow or to remove the rib or muscle causing the problem.